KRT20 and ABI2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT20	ABI2
Description		keratin 20	abl interactor 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Intermediate Filament	Nucleus Cytoplasm Cytosol Cytoskeleton Adherens Junction Lamellipodium SCAR Complex Filopodium Tip Dendritic Spine
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	DNA Binding Protein Binding Cytoskeletal Adaptor Activity SH3 Domain Binding Kinase Binding Ubiquitin Protein Ligase Binding Rac GTPase Binding Proline-rich Region Binding
	Biological Process	Apoptotic Process Cellular Response To Starvation Keratinization Intermediate Filament Organization Regulation Of Protein Secretion Cornification	Cytoskeleton Organization Actin Polymerization Or Depolymerization Viral Process Cell Migration Rac Protein Signal Transduction Peptidyl-tyrosine Phosphorylation Regulation Of Dendritic Spine Morphogenesis Lens Fiber Cell Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways		Keratinization Formation of the cornified envelope	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation VEGFA-VEGFR2 Pathway RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Height ( 19893584)	Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Butyrylcholinesterase levels ( 21862451) Diverticular disease ( 30177863) Subclinical atherosclerosis traits (other) ( 17903303) Trunk fat mass ( 28552196) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		27 interacting genes: ABI2 AMOTL2 ANKRD36BP1 C9orf16 CCDC85B COASY EIF4E2 EXOC8 FXR2 KRT13 KRT15 KRT40 KRT80 KRTAP10-7 KRTAP10-8 KRTAP10-9 NOTCH2NLA NUP62 PIK3R2 PLEKHA5 PRC1 TFIP11 TXLNA USHBP1 VIM ZC2HC1C ZC3H14	61 interacting genes: ABL1 ADAM19 ARHGAP32 ARMC7 BLOC1S6 CCDC102B CCHCR1 CDK6 CRX DTNB EFS EGLN3 EIF3H ENAH GCC1 HGS HNRNPK HOMER3 IFT20 IHO1 KHDRBS1 KIAA1217 KIFC3 KRT13 KRT15 KRT19 KRT20 KRT31 KRT33B LMO2 MCM7 MRFAP1L1 MRPL44 NCK1 NCK2 NUP62 PCM1 PIN1 PPIF PRAM1 PRKAA1 PRKAA2 PRR16 SDCBP SH3KBP1 SMARCB1 SNAP23 STAM2 TFIP11 TLE5 TRAF3IP1 TRIM32 TRIP6 VARS2 VASP VCL VPS37C WASF2 WASHC3 WIPF1 ZNF688
Entrez ID		54474	10152
HPRD ID		12193	07338
Ensembl ID		ENSG00000171431	ENSG00000138443
Uniprot IDs		P35900	A0A0C4DG21 B7Z836 E9PEZ7 F8WAL6 Q9NYB9
PDB IDs			2ED0 3P8C 4N78
Enriched GO Terms of Interacting Partners?
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