SNTG1 and DMD

Number of citations of the paper that reports this interaction (PubMedID 10747910)
32

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SNTG1	DMD
Description		syntrophin gamma 1	dystrophin
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Nucleus Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ruffle Membrane	Cell Cytosol Cytoskeleton Cell Surface Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Z Disc Cell-substrate Junction Filopodium Filopodium Membrane Protein-containing Complex Sarcolemma Costamere Neuron Projection Terminus Membrane Raft Synapse Postsynaptic Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Protein C-terminus Binding	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding
	Biological Process	Cell Communication	Regulation Of Heart Rate Cytoskeleton Organization Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Cellular Protein-containing Complex Assembly Response To Muscle Stretch Peptide Biosynthetic Process Muscle Cell Cellular Homeostasis Muscle Fiber Development Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways			Non-integrin membrane-ECM interactions Striated Muscle Contraction
Drugs
Diseases			Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD) Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM) Dilated cardiomyopathy (DCM)
GWAS		Abstraction and mental flexibility ( 31596458) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Interleukin-6 levels ( 22205395) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pulmonary function ( 17903307) Pulse pressure ( 27841878) Remission after SSRI treatment in MDD or openness ( 29559929) Response to SSRI in MDD or openness ( 29559929) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 27841878 30578418)	Ankle-brachial index ( 31388106) Anxiety in major depressive disorder ( 24047446) Body mass index ( 28892062) Influenza A (H1N1) infection ( 26379185) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Mild influenza (H1N1) infection ( 26379185) Response to anti-depressant treatment in major depressive disorder ( 22041458) Temporomandibular joint disorder ( 28081371) Waist circumference ( 28552196)
Interacting Genes		12 interacting genes: ADRA1D DGKZ DMD DTNA DTNB FGF2 KCNA4 SNAP23 STXBP3 TGFBR1 UBC VPS45	28 interacting genes: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 HNF4A KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN
Entrez ID		54212	1756
HPRD ID		16373	02303
Ensembl ID		ENSG00000147481	ENSG00000198947
Uniprot IDs		A0A024R7Y0 A0A2R8Y5T2 A0A2R8Y631 B2RA84 Q9NSN8	A0A0S2Z3B5 A0A0S2Z3J7 A7E212 P11532 Q16484 Q4G0X0
PDB IDs			1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?
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