PNN and KRT8

Number of citations of the paper that reports this interaction (PubMedID 10809736)
9

Data Source:
HPRD (in vitro, two hybrid)

		PNN	KRT8
Description		pinin, desmosome associated protein	keratin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Intermediate Filament Plasma Membrane Cell-cell Junction Membrane Nuclear Speck Desmosome Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cell-cell Junction Dystrophin-associated Glycoprotein Complex Apicolateral Plasma Membrane Nuclear Matrix Z Disc Sarcolemma Costamere Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	DNA Binding RNA Binding Structural Molecule Activity Protein Binding	Protein Binding Protein-containing Complex Binding Scaffold Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cell Adhesion	Viral Process Keratinization Tumor Necrosis Factor-mediated Signaling Pathway Sarcomere Organization Response To Hydrostatic Pressure Response To Other Organism Cell Differentiation Involved In Embryonic Placenta Development Cornification Extrinsic Apoptotic Signaling Pathway Hepatocyte Apoptotic Process
Pathways			Keratinization Formation of the cornified envelope
Drugs			Tenecteplase Copper
Diseases
GWAS			Cancer (pleiotropy) ( 27197191) Gamma glutamyl transferase levels ( 29403010) Prostate cancer ( 21743057)
Interacting Genes		17 interacting genes: CNGB1 CSNK2A1 CTBP1 CTBP2 DYNC1I2 KRT18 KRT19 KRT8 PNISR PPIG PRPF4B RNPS1 SRPK2 SRRM2 SRSF4 YWHAG ZCCHC17	35 interacting genes: ANXA1 BYSL CLK1 DEDD DMD EGFR ELOC ESR1 FBXO25 FGFR3 GRB2 HSPA5 IKBKG KPNA2 KRT13 KRT15 KRT18 KRT31 KRT38 KRT40 MAPK1 MAPK14 MAPK3 MAPK8 PKD1 PKP1 PLAT PNN PPL QRSL1 RAF1 TCHP TFIP11 TROAP WBP2
Entrez ID		5411	3856
HPRD ID		04401	01015
Ensembl ID		ENSG00000100941	ENSG00000170421
Uniprot IDs		Q9H307	P05787 Q7L4M3
PDB IDs
Enriched GO Terms of Interacting Partners?
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