Description |
promyelocytic leukemia |
MYC proto-oncogene, bHLH transcription factor |
Image |
|
|
GO Annotations |
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Accelerometer-based physical activity measurement (fraction of time with accelerations >425 milli-gravities) ( 29899525)
- Birth weight ( 31043758)
- Height ( 28552196 20881960 25282103)
- Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566)
- Insomnia symptoms (never/rarely vs. usually) ( 30804566)
- Myopia (pathological) ( 23049088)
- Paget's disease ( 21623375)
- Physical activity (overall physical activity time) ( 30531941)
|
|
Interacting Genes |
109 interacting genes:
ADH1B
ANKRD2
ARID3A
ARNT
ATF2
ATXN1
AURKA
AXIN1
BANP
BCL2
BCL6
CASP8AP2
CCNT1
CDK1
CDK2
CDK6
CHFR
CREBBP
CSNK2A1
DAXX
EGFR
EIF4E
ELF4
EP300
FOS
GATA1
GATA2
HDAC1
HDAC2
HDAC3
HHEX
HIPK2
HTT
KAT5
KAT6A
KLHL20
MAD1L1
MAPK11
MAPK14
MDM2
MED7
MXD1
MYB
MYC
NACC1
NCOA2
NCOR1
NCOR2
NFKB1
NR3C1
NR4A1
PAWR
PAXIP1
PCBD2
PIAS1
PIAS2
PIN1
PLAGL1
PLSCR1
POLR2E
PPARG
PSMA3
RARA
RB1
RBX1
RELA
RNF111
RNF125
RPL11
RXRA
SENP1
SENP2
SH3GL1
SIAH2
SIN3A
SIRT1
SKI
SLC27A2
SMAD3
SP1
SP100
SRF
STAT3
SUMO1
SUMO2
SUMO3
SUV39H1
SYNE2
TDG
TERF2IP
TGFBR1
TGFBR2
TGIF1
THRA
TOPBP1
TP53
TP63
TP73
TRIB3
TRIM24
TRIM27
TRIM69
UBE2I
UBE2U
UBE3A
USP11
ZBTB16
ZFYVE9
ZNF451
|
176 interacting genes:
ACTL6A
AKT1
APP
ARAF
ARNT
ATAD2
AURKA
AXIN1
BCL2
BIN1
BRCA1
BRD3
BTRC
CALM1
CBLC
CCAR2
CCNE1
CCNT1
CDC6
CDC73
CDCA7L
CDK1
CDK4
CDK6
CDK8
CDK9
CDKN1B
CDKN2A
CDKN2B
CDKN2C
CEBPA
CEBPB
CEP57
CIP2A
CREBBP
CSNK2A1
CSNK2A2
DACH1
DNMT3A
EFNB1
ELF3
EP300
EP400
EPHA2
ERBB2
FBXO8
FBXW7
FBXW8
FGFR4
FZR1
GCN1
GLIS1
GLIS2
GPX2
GRM1
GSK3A
GSK3B
GTF2F1
GTF2F2
GTF2I
HGF
HIF1A
HSP90AA1
ING4
KAT2A
KAT2B
KAT5
KDELR2
KDM1A
KIDINS220
LATS2
LDOC1
MAP2K1
MAP2K5
MAPK1
MAPK14
MAPK3
MAPK7
MAPK8
MAX
MDM2
MED1
MED16
MEN1
MET
MLH1
MOK
MSH2
MXD1
MXI1
MYCBP
MYCBP2
NDRG1
NEK11
NF2
NFIC
NFYB
NFYC
NMI
NONO
NOTCH3
NSD3
NUCB1
PAK2
PARP10
PDGFRA
PFDN5
PIK3CA
PLAU
PLK1
PML
PPP2CA
PRDX1
PSMC3
PTEN
RAF1
RASSF1
RB1
RBL1
RELA
RIOX2
RUVBL1
RUVBL2
SAP130
SENP2
SF3B1
SKP1
SKP2
SMAD2
SMAD3
SMARCA2
SMARCA4
SMARCB1
SMARCC1
SNIP1
SNRNP70
SOX3
SOX4
SP1
SPAG9
STK11
SUPT3H
TADA2A
TAF12
TAF1B
TAF9
TBP
TEAD2
TERT
TFAP2A
TFAP2B
TIAM1
TONSL
TP53
TP73
TRIM6
TRRAP
TSC1
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
UBB
USP2
USP22
USP36
USP37
USP7
VDR
WT1
YAF2
YBX1
YY1
ZBTB17
ZNF281
|
Entrez ID |
5371 |
4609 |
HPRD ID |
00023 |
01818 |
Ensembl ID |
ENSG00000140464
|
ENSG00000136997
|
Uniprot IDs |
P29590
|
P01106
|
PDB IDs |
1BOR
2MVW
2MWX
4WJN
4WJO
5YUF
6IMQ
6UYO
6UYP
6UYQ
6UYR
6UYS
6UYT
6UYU
6UYV
|
1A93
1EE4
1MV0
1NKP
2A93
2OR9
4Y7R
5I4Z
5I50
6C4U
6E16
6E24
6G6J
6G6K
6G6L
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|