PMCH and CPE

Number of citations of the paper that reports this interaction (PubMedID 8770919)
19

Data Source:
HPRD (in vivo)

		PMCH	CPE
Description		pro-melanin concentrating hormone	carboxypeptidase E
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Synapse	Extracellular Space Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Secretory Granule Membrane Extracellular Exosome
	Molecular Function	Melanin-concentrating Hormone Activity Type 1 Melanin-concentrating Hormone Receptor Binding	Carboxypeptidase Activity Metallocarboxypeptidase Activity Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Multicellular Organism Development Spermatogenesis Behavior Feeding Behavior Cell Differentiation	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Peptide Metabolic Process Neuropeptide Signaling Pathway Wnt Signaling Pathway Protein Processing Insulin Processing Peptide Hormone Secretion Protein Localization To Secretory Granule Protein Localization To Membrane
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Insulin processing
Drugs			Insulin Human Insulin Pork
Diseases
GWAS		Adventurousness ( 30643258) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Height ( 19893584) Number of sexual partners ( 30643258)	Pelvic organ prolapse (moderate/severe) ( 26545240) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		10 interacting genes: CPE FURIN MCHR1 MCHR2 NPY PCSK1 PCSK2 PCSK5 PCSK6 PCSK7	17 interacting genes: BDNF CCK CHD3 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A
Entrez ID		5367	1363
HPRD ID		01459	00272
Ensembl ID		ENSG00000183395	ENSG00000109472
Uniprot IDs		P20382	A0A384N679 P16870
PDB IDs
Enriched GO Terms of Interacting Partners?
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