PLXNB1 and RND1

Number of citations of the paper that reports this interaction (PubMedID 12730235)
43

Data Source:
HPRD (in vivo, in vitro)

		PLXNB1	RND1
Description		plexin B1	Rho family GTPase 1
Image
GO Annotations	Cellular Component	Semaphorin Receptor Complex Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Cytosol Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle
	Molecular Function	Transmembrane Signaling Receptor Activity GTPase Activator Activity Protein Binding Semaphorin Receptor Activity Semaphorin Receptor Binding GTPase Activating Protein Binding Signaling Receptor Activity	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Cell Adhesion Signal Transduction G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Shape Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Migration Regulation Of Cell Migration Negative Regulation Of Osteoblast Proliferation Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Ossification Involved In Bone Maturation Neuron Projection Morphogenesis Positive Regulation Of Axonogenesis Regulation Of Cytoskeleton Organization Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Bone Trabecula Morphogenesis Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Inhibitory Synapse Assembly	Cytokinesis Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Neuron Remodeling Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly
Pathways		G alpha (12/13) signalling events Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Ulcerative colitis ( 28067908)	Bipolar disorder ( 21926972)
Interacting Genes		14 interacting genes: ARHGEF11 ARHGEF12 KMT2A L1CAM MET NRP1 NRP2 PLXNA1 RAC1 RND1 RND3 SEMA4B SEMA4D SOX4	12 interacting genes: ARHGAP5 CREB3L2 FRS2 FRS3 GRB7 ID3 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212
Entrez ID		5364	27289
HPRD ID		03032	12357
Ensembl ID		ENSG00000164050	ENSG00000172602
Uniprot IDs		O43157	Q92730
PDB IDs		2JPH 2OS6 2R2O 2REX 3HM6 3OL2 3SU8 3SUA 5B4W	2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?