PLOD2 and LITAF

		PLOD2	LITAF
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	lipopolysaccharide induced TNF factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Exosome	Golgi Membrane Nucleoplasm Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Intracellular Membrane-bounded Organelle Cytoplasmic Side Of Early Endosome Membrane Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	Iron Ion Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding WW Domain Binding
	Biological Process	Response To Hypoxia Cellular Protein Modification Process Protein O-linked Glycosylation Peptidyl-lysine Hydroxylation Hydroxylysine Biosynthetic Process Oxidation-reduction Process	Regulation Of Cytokine Production Regulation Of Transcription By RNA Polymerase II Aging Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Vitamin C
Diseases		Bruck syndrome	Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Height ( 31562340) Obesity-related traits ( 23251661) Squamous cell lung carcinoma ( 28604730) Zinc levels ( 26025379)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Colorectal or endometrial cancer ( 26621817) Crohn's disease ( 28067908) Gallstone disease ( 30504769) Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908 23128233) QT interval ( 23166209 30679814 29213071 24952745 19305408 19305409) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482)
Interacting Genes		6 interacting genes: CENPF CLSTN2 LITAF LYPLA1 NUCB1 WWTR1	15 interacting genes: ATXN1 BAG3 CALCOCO2 COMT HGS ITCH NEDD4 OPTN PLOD2 RADIL REEP6 SMAD2 STAM2 STAT6 UBQLN1
Entrez ID		5352	9516
HPRD ID		03519	10354
Ensembl ID		ENSG00000152952	ENSG00000189067
Uniprot IDs		O00469	Q99732
PDB IDs
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