PLCB2 and MAP2K6

  • Number of citations of the paper that reports this interaction (PubMedID 12054652)
  • 2
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

PLCB2

MAP2K6

Description phospholipase C beta 2 mitogen-activated protein kinase kinase 6
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872)
  • Optic disc size ( 31809533)
  • Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482)
  • Response to TNF-alpha inhibitors in rheumatoid arthritis ( 22569225)
  • Waist-hip ratio ( 28552196)
Interacting Genes 7 interacting genes: GNAQ MAP2K3 MAP2K6 SLC9A3R1 SNCA TRPC3 TRPM7 37 interacting genes: AKT1 BECN1 BRAF CCND2 CDKN2B DCTN1 EPHA2 FBXO7 FGFR4 GLIS2 HGF HRAS LRRK2 MAP2K3 MAP2K4 MAP2K5 MAP3K20 MAP3K4 MAP3K5 MAP3K7 MAPK1 MAPK12 MAPK13 MAPK14 MAPKAPK2 MLH1 PKN1 PLCB2 RAF1 RASSF1 RELA SMAD7 STAT4 STK11 TAOK2 TLR3 TRAF6
Entrez ID 5330 5608
HPRD ID 04985 03155
Ensembl ID ENSG00000137841 ENSG00000108984
Uniprot IDs Q00722 Q59F77 Q9BVT6 A0A024R8K3 A8K3Y2 P52564
PDB IDs 2FJU 2ZKM 2Y8O 3ENM 3FME 3VN9 5ETF
Enriched GO Terms of Interacting Partners?
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