PIGA and PIGQ

Number of citations of the paper that reports this interaction (PubMedID 9463366)
48

Data Source:
HPRD (in vitro)

		PIGA	PIGQ
Description		phosphatidylinositol glycan anchor biosynthesis class A	phosphatidylinositol glycan anchor biosynthesis class Q
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding UDP-glycosyltransferase Activity Phosphatidylinositol N-acetylglucosaminyltransferase Activity	Phosphatidylinositol N-acetylglucosaminyltransferase Activity
	Biological Process	GPI Anchor Biosynthetic Process Positive Regulation Of Metabolic Process Preassembly Of GPI Anchor In ER Membrane Cellular Response To Leukemia Inhibitory Factor	Carbohydrate Metabolic Process Preassembly Of GPI Anchor In ER Membrane
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases		Paroxysmal nocturnal hemoglobinuria (PNH)
GWAS			Disc degeneration (lumbar) ( 22993228) Mean corpuscular hemoglobin concentration ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		4 interacting genes: DPM2 PIGH PIGQ PIGY	4 interacting genes: PIGA PIGC PIGH SMAD1
Entrez ID		5277	9091
HPRD ID		02410	09307
Ensembl ID		ENSG00000165195	ENSG00000007541
Uniprot IDs		A0A2K4ZA02 P37287	B2RAU6 Q9BRB3
PDB IDs
Enriched GO Terms of Interacting Partners?
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