ATP6V0C and SMIM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ATP6V0C	SMIM3
Description		ATPase H+ transporting V0 subunit c	small integral membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Insulin Receptor Signaling Pathway Viral Process Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs
Diseases
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)
Interacting Genes		11 interacting genes: ARF6 CERS2 CLIC1 CREB3 EDA LMNA MARK3 MDFI MSR1 PSMA3 SMIM3	10 interacting genes: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1 SFTPC TRIM14
Entrez ID		527	85027
HPRD ID		00162	12212
Ensembl ID		ENSG00000185883	ENSG00000256235
Uniprot IDs		P27449	Q9BZL3
PDB IDs
Enriched GO Terms of Interacting Partners?
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