PHF1 and BRD2

		PHF1	BRD2
Description		PHD finger protein 1	bromodomain containing 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome ESC/E(Z) Complex Site Of Double-strand Break	Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Methylated Histone Binding Metal Ion Binding	Chromatin Binding Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation	Neural Tube Closure Nucleosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatogenesis Viral Process
Pathways		PRC2 methylates histones and DNA	RUNX3 regulates p14-ARF
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)	Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 28008999) Feeling nervous ( 29500382) Inflammatory bowel disease ( 28008999) Ulcerative colitis ( 28008999)
Interacting Genes		24 interacting genes: ATXN7L1 BIRC7 BRD2 CALCOCO2 EZH2 H3C1 H3C10 H3C11 H3C12 H3C2 H3C3 H3C6 H3C7 H3C8 H4C1 HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14	17 interacting genes: CDC42EP4 CLCN2 DDR1 E2F1 E2F2 ECEL1 H2BC21 H2BU1 H4-16 HLA-DQA1 HOXC6 PHF1 PRNP PSMB9 RAC2 SPOP TBP
Entrez ID		5252	6046
HPRD ID		04195	03326
Ensembl ID		ENSG00000112511	ENSG00000204256
Uniprot IDs		A0A140VJR4 A0A1U9X8A3 O43189	A0A024RCR5 A0A1U9X7A8 P25440 X5CF57
PDB IDs		2E5P 2M0O 4HCZ 5XFN 5XFO 5XFP	1X0J 2DVQ 2DVR 2DVS 2DVV 2E3K 2G4A 2YDW 2YEK 3AQA 3ONI 4A9E 4A9F 4A9H 4A9I 4A9J 4A9M 4A9N 4A9O 4AKN 4ALG 4ALH 4J1P 4MR5 4MR6 4QEU 4QEV 4QEW 4UYF 4UYG 4UYH 5BT5 5DFB 5DFC 5DFD 5DW1 5EK9 5HEL 5HEM 5HEN 5HFQ 5IBN 5IG6 5N2L 5O38 5O39 5O3A 5O3B 5O3C 5O3D 5O3E 5O3F 5O3G 5O3H 5O3I 5U5S 5U6V 5UEW 5XHE 5XHK 6CUI 6DB0 6DBC 6DDI 6DDJ 6E6J 6FFE 6FFF 6FFG 6I80 6I81 6K04 6K05 6MO7 6MO8 6MO9 6MOA
Enriched GO Terms of Interacting Partners?
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