CFP and TRIP13

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		CFP	TRIP13
Description		complement factor properdin	thyroid hormone receptor interactor 13
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Tertiary Granule Lumen	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Protein Binding	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Regulation Of Complement Activation Defense Response To Bacterium Neutrophil Degranulation	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Regulation Of Nucleic Acid-templated Transcription
Pathways		Alternative complement activation Activation of C3 and C5 Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins Neutrophil degranulation Regulation of Complement cascade
Drugs
Diseases		Alternative complement pathway component defects, including the following four diseases: Factor B deficiency; Factor D deficiency; Factor H deficiency; Properdin deficiency
GWAS			Pancreatic cancer ( 25086665)
Interacting Genes		4 interacting genes: C3 CFB MTOR TRIP13	83 interacting genes: ADAM15 AMDHD2 ARL11 ARSA ASB13 BUB1B C11orf54 C4orf33 CARD14 CD99 CDC20 CFP COMT CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 INTS11 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 NTAQ1 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA PRKN QARS1 RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR ZNF34 ZNF655
Entrez ID		5199	9319
HPRD ID		02308	05145
Ensembl ID		ENSG00000126759	ENSG00000071539
Uniprot IDs		A0A0S2Z4I5 P27918	Q15645
PDB IDs		1W0R 1W0S 6RUR 6RUS 6RUV 6RV6 6S08 6S0A 6S0B 6SEJ	5VQ9 5VQA 5WC2 6F0X
Enriched GO Terms of Interacting Partners?
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