PEX12 and PEX10

Number of citations of the paper that reports this interaction (PubMedID 10562279)
27

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro, in vivo)

		PEX12	PEX10
Description		peroxisomal biogenesis factor 12	peroxisomal biogenesis factor 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Peroxisomal Importomer Complex	Peroxisome Peroxisomal Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Protein Monoubiquitination Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Red cell distribution width ( 27863252 28957414)	Body mass index ( 26426971) Non-obstructive azoospermia ( 22197933)
Interacting Genes		3 interacting genes: PEX10 PEX19 PEX5	10 interacting genes: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I
Entrez ID		5193	5192
HPRD ID		03455	04175
Ensembl ID		ENSG00000108733	ENSG00000157911
Uniprot IDs		O00623	A0A024R068 A0A024R0A4 O60683
PDB IDs
Enriched GO Terms of Interacting Partners?
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