WBP11 and RUNX1T1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WBP11	RUNX1T1
Description		WW domain binding protein 11	RUNX1 partner transcriptional co-repressor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Nuclear Matrix
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding	DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome RRNA Processing MRNA Cis Splicing, Via Spliceosome	Generation Of Precursor Metabolites And Energy Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases			Acute myeloid leukemia (AML)
GWAS			Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Number of sexual partners ( 30643258) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Plasma anti-thyroglobulin levels ( 29678681) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		29 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 NCK2 NOD2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SRC TESC TRAF4 TRIP10 VIM WBP4	52 interacting genes: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CBY2 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 IHO1 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRKAR2A SIN3A SPEN SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		51729	862
HPRD ID		18293	00590
Ensembl ID		ENSG00000084463	ENSG00000079102
Uniprot IDs		A0A024RAW9 Q9Y2W2	A0A087WWT6 A0A0A0MSU1 B2R6I9 Q06455 W8FW32
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?
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