UIMC1 and ZMYM3

Number of citations of the paper that reports this interaction (PubMedID 28242625)
17

Data Source:
BioGRID (pull down)

		UIMC1	ZMYM3
Description		ubiquitin interaction motif containing 1	zinc finger MYM-type containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body BRCA1-A Complex	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Histone Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding
	Biological Process	Double-strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Ionizing Radiation Protein Deubiquitination Positive Regulation Of DNA Repair Negative Regulation Of Transcription, DNA-templated Histone H2A K63-linked Deubiquitination Signal Transduction Involved In G2 DNA Damage Checkpoint	Regulation Of Transcription By RNA Polymerase II Cytoskeleton Organization Multicellular Organism Development Regulation Of Cell Morphogenesis
Pathways		Metalloprotease DUBs Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Nonhomologous End-Joining (NHEJ) Processing of DNA double-strand break ends G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Menarche and menopause (age at onset) ( 19448621) Menopause (age at onset) ( 22267201 26414677 29773799) Uterine fibroids ( 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		20 interacting genes: ABRAXAS1 ATP8A2 BRCC3 CEP57 CREBBP DVL2 ECPAS ESR1 FANCG H2AC20 INO80B MDC1 NR6A1 SKIL TP53 UBB UBC USP13 WBP2 ZMYM3	8 interacting genes: ABRAXAS1 APP CDK6 GTF2I PDZD11 SUMO1 SUMO2 UIMC1
Entrez ID		51720	9203
HPRD ID		11482	02088
Ensembl ID		ENSG00000087206	ENSG00000147130
Uniprot IDs		A0A024R7R0 Q96RL1	A8K3Z7 Q14202
PDB IDs		2MKF 2MKG 2N9E 2RR9
Enriched GO Terms of Interacting Partners?
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