- and CYP4F2

Number of citations of the paper that reports this interaction (PubMedID 10660572)
57

Data Source:
BioGRID (enzymatic study, biochemical)

		-	CYP4F2
Description		pigment disorder, reticulate	cytochrome P450 family 4 subfamily F member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Endoplasmic Reticulum Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function		Iron Ion Binding Protein Binding Arachidonic Acid Epoxygenase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Alkane 1-monooxygenase Activity Heme Binding Leukotriene-B4 20-monooxygenase Activity Arachidonic Acid Omega-hydroxylase Activity Alpha-tocopherol Omega-hydroxylase Activity Tocotrienol Omega-hydroxylase Activity Aromatase Activity
	Biological Process		Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Renal Water Homeostasis Pressure Natriuresis Icosanoid Metabolic Process Leukotriene Metabolic Process Blood Coagulation Regulation Of Blood Pressure Drug Metabolic Process Arachidonic Acid Metabolic Process Epoxygenase P450 Pathway Negative Regulation Of Icosanoid Secretion Positive Regulation Of Icosanoid Secretion Leukotriene B4 Catabolic Process Vitamin E Metabolic Process Menaquinone Catabolic Process Phylloquinone Catabolic Process Vitamin K Catabolic Process Sodium Ion Homeostasis Oxidation-reduction Process Omega-hydroxylase P450 Pathway
Pathways			Fatty acids Miscellaneous substrates Eicosanoids Synthesis of Leukotrienes (LT) and Eoxins (EX) Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
Drugs
Diseases
GWAS		HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)	Acenocoumarol maintenance dosage ( 19578179) Circulating phylloquinone levels ( 25411281) Metabolite levels ( 23281178) Response to Vitamin E supplementation ( 22437554) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Vitamin E levels ( 21729881) Warfarin maintenance dose ( 20833655 19300499)
Interacting Genes		1 interacting genes: CYP4F2	3 interacting genes: - CHMP2A CREB3
Entrez ID		5171	8529
HPRD ID			05112
Ensembl ID			ENSG00000186115
Uniprot IDs			P78329
PDB IDs
Enriched GO Terms of Interacting Partners?
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