LUC7L2 and OFD1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LUC7L2	OFD1
Description		LUC7 like 2, pre-mRNA splicing factor	OFD1 centriole and centriolar satellite protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	U1 SnRNP Nuclear Speck U2-type Prespliceosome	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Membrane Centriolar Satellite Ciliary Basal Body
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding
	Biological Process	MRNA Splice Site Selection	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Axoneme Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases			Oral-facial-digital syndrome 1 Joubert syndrome
GWAS		Diisocyanate-induced asthma ( 25918132)
Interacting Genes		51 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 PABPC4 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRSF6 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10	8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6
Entrez ID		51631	8481
HPRD ID		17456	02162
Ensembl ID		ENSG00000146963	ENSG00000046651
Uniprot IDs		Q9Y383	A6NF31 E9KL37 O75665
PDB IDs
Enriched GO Terms of Interacting Partners?
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