CHMP5 and CHMP4A

Number of citations of the paper that reports this interaction (PubMedID 26344197)
117

Data Source:
BioGRID (biochemical)
HPRD (two hybrid)

		CHMP5	CHMP4A
Description		charged multivesicular body protein 5	charged multivesicular body protein 4A
Image
GO Annotations	Cellular Component	Cell Nucleus Cytosol Endosome Membrane Extracellular Exosome	ESCRT III Complex Cell Nucleus Cytoplasm Endosome Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Membrane Invagination Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly
Pathways		Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)	Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		17 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 NUP98 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91	12 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		51510	29082
HPRD ID		15408	16597
Ensembl ID		ENSG00000086065	ENSG00000254505
Uniprot IDs		Q9NZZ3	Q9BY43
PDB IDs		2LXM 3ULY 3UM0 3UM1 3UM2 4TXR	3C3O 5MK1
Enriched GO Terms of Interacting Partners?
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