HSD17B7 and DTYMK

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		HSD17B7	DTYMK
Description		hydroxysteroid 17-beta dehydrogenase 7	deoxythymidylate kinase
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Cytosol
	Molecular Function	3-keto Sterol Reductase Activity Estradiol 17-beta-dehydrogenase Activity	Nucleoside Diphosphate Kinase Activity Thymidylate Kinase Activity ATP Binding Uridylate Kinase Activity
	Biological Process	Cholesterol Biosynthetic Process Estrogen Biosynthetic Process Nervous System Development Cell Differentiation Embryonic Skeletal System Development Oxidation-reduction Process	Nucleoside Diphosphate Phosphorylation DUDP Biosynthetic Process DTDP Biosynthetic Process DTTP Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Response To Estrogen Myoblast Differentiation Thymidine Biosynthetic Process Response To Cadmium Ion Nucleoside Monophosphate Phosphorylation Cellular Response To Growth Factor Stimulus
Pathways		Cholesterol biosynthesis	Interconversion of nucleotide di- and triphosphates
Drugs		NADH	Thymidine-5'-Phosphate 2',3'-Dideoxythymidine-5'-Monophosphate Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] Ester Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] Ester P1-(5'-Adenosyl)P5-(5'-Thymidyl)Pentaphosphate 3'-Azido-3'-Deoxythymidine-5'-Monophosphate P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))Pentaphosphate Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Dupuytren's disease ( 28886342)	Diverticular disease ( 30177863) Prostate cancer ( 23535732)
Interacting Genes		6 interacting genes: BRSK1 CA1 DTYMK GORAB GPAT4 VKORC1	1 interacting genes: HSD17B7
Entrez ID		51478	1841
HPRD ID		05996	01773
Ensembl ID		ENSG00000132196	ENSG00000168393
Uniprot IDs		A0A024R913 P56937 Q5T248 Q9H9C0	P23919 Q53F55 Q6FGU2
PDB IDs			1E2D 1E2E 1E2F 1E2G 1E2Q 1E98 1E99 1E9A 1E9B 1E9C 1E9D 1E9E 1E9F 1NMX 1NMY 1NMZ 1NN0 1NN1 1NN3 1NN5 2XX3
Enriched GO Terms of Interacting Partners?
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