AMOTL2 and CHCHD3

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		AMOTL2	CHCHD3
Description		angiomotin like 2	coiled-coil-helix-coiled-coil-helix domain containing 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane MICOS Complex Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Phosphatase Binding Molecular Adaptor Activity
	Biological Process	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling	Negative Regulation Of Transcription By RNA Polymerase II Inner Mitochondrial Membrane Organization Mitochondrial Fusion Cristae Formation
Pathways		Signaling by Hippo	Mitochondrial protein import Cristae formation
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)	Chronotype ( 30696823) Food allergy ( 29030101) Intercellular adhesion molecule 1 (red blood cell fatty acid level interaction) ( 28820441) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Smoking status (ever vs never smokers) ( 30643258) Urinary potassium excretion ( 31409800)
Interacting Genes		57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT	24 interacting genes: AASS AMOTL2 BLZF1 CALCOCO2 CBY2 CCDC33 CCDC85B FANCL GMCL2 GOLGA2 KRT40 KRTAP4-12 LZTS2 NOTCH2NLA NUDT3 PDE4DIP RAB3IP RPGRIP1 SAMM50 SPAG5 SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		51421	54927
HPRD ID		16485	13044
Ensembl ID		ENSG00000114019	ENSG00000106554
Uniprot IDs		Q9Y2J4	A4D1N4 B7Z1X9 C9JRZ6 Q9NX63
PDB IDs
Enriched GO Terms of Interacting Partners?
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