UBR5 and CSPP1

Number of citations of the paper that reports this interaction (PubMedID 29742019)
6

Data Source:
BioGRID (protein complementation assay)

		UBR5	CSPP1
Description		ubiquitin protein ligase E3 component n-recognin 5	centrosome and spindle pole associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Spindle Pole Cytoplasm Centrosome Spindle Microtubule
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Protein Import Into Nucleus Progesterone Receptor Signaling Pathway Protein K48-linked Ubiquitination Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair	Positive Regulation Of Cytokinesis Positive Regulation Of Cell Division
Pathways
Drugs
Diseases
GWAS		Chromosomal aberration frequency (total) ( 31586183) Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209) Type 2 diabetes (age of onset) ( 28060188)	Hip circumference adjusted for BMI ( 28552196)
Interacting Genes		31 interacting genes: BARD1 BUB3 CIB1 CSPP1 DYRK2 ERG GSK3B KPNA1 KPNA2 KPNB1 MAPK1 MOAP1 NR1I2 OTUD5 PAIP1 PAIP2 PCK1 PGR SATB1 SMAD2 SOX2 TCEA1 TOPBP1 TXNIP UBC UBE2A UBE2B UBE2D2 UBE2D3 UBE2L3 ZNF207	6 interacting genes: GOLGA2 MRFAP1L1 RINT1 RPGRIP1 TRIM14 UBR5
Entrez ID		51366	79848
HPRD ID		06436	07991
Ensembl ID		ENSG00000104517	ENSG00000104218
Uniprot IDs		O95071	Q1MSJ5 Q9H688
PDB IDs		1I2T 2QHO 3PT3
Enriched GO Terms of Interacting Partners?
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