GMIP and GEM

Number of citations of the paper that reports this interaction (PubMedID 12093360)
21

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		GMIP	GEM
Description		GEM interacting protein	GTP binding protein overexpressed in skeletal muscle
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane	Cell Nucleus Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Spindle Midzone Mitotic Spindle
	Molecular Function	GTPase Activator Activity Protein Binding Metal Ion Binding	Magnesium Ion Binding GTPase Activity Calcium Channel Regulator Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Negative Regulation Of GTPase Activity Intracellular Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Mitotic Cell Cycle Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Chromosome Organization Metaphase Plate Congression Negative Regulation Of High Voltage-gated Calcium Channel Activity
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Schizophrenia ( 23974872) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)	Carotid plaque burden ( 28282560) Coronary artery disease ( 29212778) Pulse pressure ( 30578418)
Interacting Genes		2 interacting genes: GEM RHOA	41 interacting genes: A2M AHCYL1 APOH BLZF1 BMP1 CALM1 CCDC102B CLDN15 CLEC4G COG8 CTSL DEUP1 GMIP GOLGA2 IKZF3 INO80E KCTD9 KLC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 LZTS2 NDUFAF3 NDUFS8 NOTCH2NLA PDLIM7 PNMA1 RNF7 RUNDC3A SDHB SSX2IP TCF4 TFIP11 TRAF1 TRIM23 TRIM27 TRIM54 VTN YBEY YWHAB
Entrez ID		51291	2669
HPRD ID		11005	11553
Ensembl ID		ENSG00000089639	ENSG00000164949
Uniprot IDs		A0A024R7N1 B4DLZ1 Q9P107	A0A024R9F5 P55040
PDB IDs		3QWE	2CJW 2G3Y 2HT6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?