GOLM1 and KCNE3

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		GOLM1	KCNE3
Description		golgi membrane protein 1	potassium voltage-gated channel subfamily E regulatory subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Lumen Golgi Apparatus Integral Component Of Plasma Membrane	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Vesicle Neuronal Cell Body Membrane Perikaryon Membrane Raft
	Molecular Function	Protein Binding	Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Ion Channel Binding Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Nucleus Organization Regulation Of Lipid Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process	Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Voltage-gated Potassium Channel Activity Negative Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Phase 3 - rapid repolarisation Phase 2 - plateau phase
Drugs
Diseases			Brugada syndrome (BRS)
GWAS		Blood protein levels ( 30072576) Logical memory (delayed recall) in normal cognition ( 29274321)	Corneal astigmatism ( 22144915) Neuritic plaque ( 31497858)
Interacting Genes		27 interacting genes: B3GNT4 C1orf174 CIAO1 CLK1 DCK DCTN2 DEXI EFTUD2 EIF2B3 EIF3J ELAC2 FLOT1 FTH1 GEMIN7 GRIK5 KCNE3 LSM12 MED22 NIPSNAP3A NRSN2 RACK1 RPA2 RPL13A SLC40A1 SYT1 TLE1 ZFAND3	10 interacting genes: C11orf68 EEF1A1 GAPDH GOLM1 KIF5A LRIF1 POLA2 QARS1 RASSF1 SLC44A1
Entrez ID		51280	10008
HPRD ID		08428	07256
Ensembl ID		ENSG00000135052	ENSG00000175538
Uniprot IDs		B3KNK9 Q8NBJ4	Q6IAE6 Q9Y6H6
PDB IDs			2NDJ
Enriched GO Terms of Interacting Partners?
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