DNAJC27 and RAB10

		DNAJC27	RAB10
Description		DnaJ heat shock protein family (Hsp40) member C27	RAB10, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus	Golgi Membrane Exocyst Endosome Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Synaptic Vesicle Endomembrane System Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network
	Molecular Function	GTPase Activity Protein Binding GTP Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Intracellular Protein Transport Rab Protein Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of MAPK Export From Nucleus	Intracellular Protein Transport Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Axonogenesis Protein Secretion Vesicle-mediated Transport Endosomal Transport Regulation Of Exocytosis Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Rab Protein Signal Transduction Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Neutrophil Degranulation Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Body mass index ( 22344219 26426971 28892062) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Height ( 20881960 31562340) Inflammatory bowel disease ( 28067908) Obese vs. thin ( 30677029) Obesity (extreme) ( 30677029) Pre-treatment viral load in HIV-1 infection ( 31219150) Pubertal anthropometrics ( 23449627) Type 1 diabetes ( 21980299)	Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000)
Interacting Genes		2 interacting genes: RAB10 TFCP2	17 interacting genes: APP ATRAID DNAJC27 EFR3B ENOPH1 EVI5L GPN1 IFT172 MICAL1 MTNR1A PLP2 PPBP PREB RABIF RIMS1 SEPTIN9 TP53I3
Entrez ID		51277	10890
HPRD ID		15221	06692
Ensembl ID		ENSG00000115137	ENSG00000084733
Uniprot IDs		Q9NZQ0	P61026
PDB IDs		2YS8	5LPN 5SZJ
Enriched GO Terms of Interacting Partners?
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