UBAP1 and PTPN23

Number of citations of the paper that reports this interaction (PubMedID 21757351)
41

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down, two hybrid, x-ray crystallography, unspecified method)

		UBAP1	PTPN23
Description		ubiquitin associated protein 1	protein tyrosine phosphatase non-receptor type 23
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GO Annotations	Cellular Component	ESCRT I Complex Cytoplasm Cytosol Plasma Membrane Endosome Membrane Intracellular Membrane-bounded Organelle Host Cell	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Nuclear Body Ciliary Basal Body Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin Binding	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding
	Biological Process	Protein Transport Endosomal Transport Viral Life Cycle Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Transport Of Virus	Negative Regulation Of Epithelial Cell Migration Protein Transport Endocytic Recycling Peptidyl-tyrosine Dephosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Early Endosome To Late Endosome Transport Cilium Assembly Positive Regulation Of Wnt Protein Secretion Cellular Response To Cytokine Stimulus Positive Regulation Of Homophilic Cell Adhesion Positive Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy	Interleukin-37 signaling
Drugs
Diseases
GWAS		Creatine kinase levels ( 29403010) Pulse pressure ( 30224653)	C-reactive protein levels ( 30388399) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		5 interacting genes: ITGA5 MAP3K1 PPIC PTPN23 UBC	10 interacting genes: ALG2 CEP55 CHMP4B DDX24 LRRK2 NOTCH2NLA PSMA3 TRIM27 UBAP1 UBC
Entrez ID		51271	25930
HPRD ID		15597	05959
Ensembl ID		ENSG00000165006	ENSG00000076201
Uniprot IDs		Q9NZ09	B4DST5 Q9H3S7
PDB IDs		1WGN 4AE4 5LM1	3RAU 5CRU 5CRV 5LM1 5LM2 5MJY 5MJZ 5MK0 5MK1 5MK2 5MK3
Enriched GO Terms of Interacting Partners?
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