CDKL3 and ZBTB14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDKL3	ZBTB14
Description		cyclin dependent kinase like 3	zinc finger and BTB domain containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Cellular Protein Modification Process Protein Phosphorylation Negative Regulation Of Axon Extension Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Dendrite Extension	Negative Regulation Of Transcription By RNA Polymerase II Heart Valve Development Cardiac Septum Development Negative Regulation Of Transcription, DNA-templated Coronary Vasculature Development
Pathways
Drugs
Diseases
GWAS		Eosinophil counts ( 27863252) Moderate-to-late spontaneous preterm birth ( 31194736)	Cerebral amyloid deposition (PET imaging) ( 26252872)
Interacting Genes		18 interacting genes: APP ATG4A DNAAF6 FXR2 GGA1 GOLGA2 KASH5 KRTAP10-9 LRRK2 LZTS2 MDFI MTUS2 SNRNP70 SRPK1 TRIM27 TTF2 ZBTB14 ZBTB8A	37 interacting genes: AP1M1 ATP5PO BAZ2B BYSL CBX8 CDK16 CDKL3 CEP19 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 NAA10 PIN1 PNKP POLR2L PRMT1 RNPS1 RPL9 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TXN2 ZBTB21 ZCCHC10 ZMAT2
Entrez ID		51265	7541
HPRD ID		09766	03674
Ensembl ID		ENSG00000006837	ENSG00000198081
Uniprot IDs		B4DX41 Q8IVW4	B2R850 O43829
PDB IDs		3ZDU
Enriched GO Terms of Interacting Partners?
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