HSPA14 and DNAJC2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vitro)

		HSPA14	DNAJC2
Description		heat shock protein family A (Hsp70) member 14	DnaJ heat shock protein family (Hsp40) member C2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Ribosome Polysome Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	Protein Binding ATP Binding ATPase Activity Heat Shock Protein Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Unfolded Protein Binding Misfolded Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding RNA Binding Protein Binding Hsp70 Protein Binding Histone Binding Ubiquitin Modification-dependent Histone Binding
	Biological Process	Cytoplasmic Translation Regulation Of Translational Fidelity Response To Unfolded Protein Cellular Response To Unfolded Protein Protein Refolding 'de Novo' Cotranslational Protein Folding Chaperone Cofactor-dependent Protein Refolding	DNA Replication Chromatin Organization Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription, DNA-templated 'de Novo' Cotranslational Protein Folding Regulation Of Cellular Response To Heat Negative Regulation Of DNA Biosynthetic Process
Pathways		Regulation of HSF1-mediated heat shock response	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		6 interacting genes: BARD1 BRCA1 DNAJC2 FAM107A PAXIP1 STIP1	2 interacting genes: H2AC18 HSPA14
Entrez ID		51182	27000
HPRD ID		07021	19072
Ensembl ID		ENSG00000187522	ENSG00000105821
Uniprot IDs		B0YIZ1 Q0VDF9 Q8TAQ0	Q99543
PDB IDs			2M2E 6CGH
Enriched GO Terms of Interacting Partners?
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