HSD17B14 and TBC1D22B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		HSD17B14	TBC1D22B
Description		hydroxysteroid 17-beta dehydrogenase 14	TBC1 domain family member 22B
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding Testosterone 17-beta-dehydrogenase (NADP+) Activity	GTPase Activator Activity Protein Binding Rab GTPase Binding 14-3-3 Protein Binding
	Biological Process	Estrogen Biosynthetic Process Steroid Catabolic Process Oxidation-reduction Process	Intracellular Protein Transport Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Estrogen biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)	Acne (severe) ( 24927181) Platelet count ( 27863252)
Interacting Genes		16 interacting genes: CA8 CDKN2D CYTOR DDIT3 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 PHF1 PSMA1 SNAPC3 SNRPC SREK1IP1 TBC1D22B	23 interacting genes: CALCOCO2 CCDC57 CDR2 DAPK1 DEUP1 FXR2 GOLGA2 HSD17B14 IKZF3 KRT40 LRRK2 MFHAS1 PNMA5 RBM10 SIAH1 SORBS3 TACC3 TEX11 TP53BP2 TRIM23 TRIM27 TRIM54 VPS52
Entrez ID		51171	55633
HPRD ID		16801	15475
Ensembl ID		ENSG00000087076	ENSG00000065491
Uniprot IDs		A0A140VJH8 Q9BPX1	Q9NU19
PDB IDs		1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO	6D0S
Enriched GO Terms of Interacting Partners?
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