ING4 and NAV2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ING4	NAV2
Description		inhibitor of growth family member 4	neuron navigator 2
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytosol Intermediate Filament Cytoskeleton	Interstitial Matrix Nucleoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Methylated Histone Binding Metal Ion Binding	DNA Helicase Activity Protein Binding ATP Binding Heparin Binding
	Biological Process	DNA Replication Protein Acetylation Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Arrest Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Growth Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Systemic Arterial Blood Pressure By Baroreceptor Feedback Nervous System Development Sensory Perception Of Sound Sensory Perception Of Smell Locomotory Behavior Optic Nerve Development Glossopharyngeal Nerve Development Vagus Nerve Development Neurogenesis DNA Duplex Unwinding
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS			Adverse response to drug ( 30420678) Atrial fibrillation ( 30061737 29892015) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) Coronary artery aneurysm in Kawasaki disease ( 27171184) General cognitive ability ( 29844566) Hepatitis ( 25705159) Low susceptibility to hepatitis C infection ( 31206233) Macular thickness ( 30535121) Monobrow ( 27182965) Obesity-related traits ( 23251661) PR interval ( 30046033) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Smoking initiation (ever regular vs never regular) ( 30679032) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306) Waist circumference ( 28552196)
Interacting Genes		16 interacting genes: CDC34 EGLN1 EP300 H3-4 H3C1 HNRNPD HOXB9 KAT7 MAPK8IP2 MSX1 MYC NAV2 RELA SUV39H1 TLX3 TP53	12 interacting genes: ADAT2 APC CFAP58 ING4 ING5 MORF4L1 PIAS2 PRPF3 PSTPIP1 RBM15 RBM15B RRAS
Entrez ID		51147	89797
HPRD ID		09774	07385
Ensembl ID		ENSG00000111653	ENSG00000166833
Uniprot IDs		Q9UNL4	A7E2D6 Q8IVL1
PDB IDs		2K1J 2M1R 2PNX 2VNF 4AFL	2YRN
Enriched GO Terms of Interacting Partners?
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