TRAPPC12 and TRAPPC6A

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, two hybrid)

		TRAPPC12	TRAPPC6A
Description		trafficking protein particle complex 12	trafficking protein particle complex 6A
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Cell Nucleus Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm	Golgi Membrane Endoplasmic Reticulum Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex
	Molecular Function	Endopeptidase Activity Protein Binding	Protein Binding
	Biological Process	Proteolysis ER To Golgi Vesicle-mediated Transport Golgi Organization Metaphase Plate Congression Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore	ER To Golgi Vesicle-mediated Transport Regulation Of GTPase Activity COPII Vesicle Coating Melanosome Assembly
Pathways		RAB GEFs exchange GTP for GDP on RABs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs			S-PALMITOYL-L-CYSTEINE
Diseases
GWAS		Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411)	Alzheimer's disease (onset between ages 58 and 79) ( 30979435) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Cerebrospinal fluid AB1-42 levels ( 28247064)
Interacting Genes		9 interacting genes: FBXO7 MTDH TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9	15 interacting genes: CRYAB EFS HOXA1 IKZF3 RAB3IP RAD54B TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3 TRAPPC3L TRAPPC6B ZMIZ2 ZNRD2
Entrez ID		51112	79090
HPRD ID		15580	14503
Ensembl ID		ENSG00000171853	ENSG00000007255
Uniprot IDs		A0A0J9YXQ9 Q8WVT3	B7TZ90 O75865
PDB IDs			2C0J 2J3T
Enriched GO Terms of Interacting Partners?
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