APIP and PDZD4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		APIP	PDZD4
Description		APAF1 interacting protein	PDZ domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cell Cortex
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity
	Biological Process	Apoptotic Process L-methionine Salvage From S-adenosylmethionine L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptosis Regulation Of ERK1 And ERK2 Cascade
Pathways		Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		17 interacting genes: APAF1 CFAP206 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 ZBTB25	3 interacting genes: APIP APP GFI1B
Entrez ID		51074	57595
HPRD ID		14725	06601
Ensembl ID		ENSG00000149089	ENSG00000067840
Uniprot IDs		Q96GX9	B3KVR9 B3KW03 D3DWW0 Q17RL8 Q76G19
PDB IDs		4M6R
Enriched GO Terms of Interacting Partners?
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