PBX2 and HOXA9

Number of citations of the paper that reports this interaction (PubMedID 10082572)
73

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vivo, in vitro)

		PBX2	HOXA9
Description		PBX homeobox 2	homeobox A9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Transcription Factor Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding
	Biological Process	Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II	Transcription, DNA-templated Multicellular Organism Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Embryonic Forelimb Morphogenesis Endothelial Cell Activation Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Uterus Development Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Asthma ( 21804548 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947) Crohn's disease ( 23266558) Inflammatory bowel disease ( 28067908) Moderate to vigorous physical activity levels ( 29899525) Prostate cancer ( 23535732) Ulcerative colitis ( 28067908)	Hypertension ( 30487518) Mean arterial pressure ( 30487518) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		22 interacting genes: BAIAP2 BLOC1S1 CARD9 CCDC88B CENPBD1 COPS6 DCTN3 ELP1 HOXA1 HOXA9 HOXB8 MCRS1 MTREX NEU1 NUP62 PBX1 PKNOX1 RPL4 RPS6KC1 SMYD3 UBE2E1 ZDHHC7	14 interacting genes: CREBBP CUL4A JUN MEIS1 MEIS2 NFKBIA PBX1 PBX2 PBX3 PLSCR1 RBPMS SMAD2 SMAD4 TRIP6
Entrez ID		5089	3205
HPRD ID		08890	00844
Ensembl ID		ENSG00000204304	ENSG00000078399
Uniprot IDs		A0A024RCR3 P40425	P31269
PDB IDs
Enriched GO Terms of Interacting Partners?
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