ITSN2 and SNAP29

Number of citations of the paper that reports this interaction (PubMedID 22558309)
18

Data Source:
BioGRID (two hybrid)

		ITSN2	SNAP29
Description		intersectin 2	synaptosome associated protein 29
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GO Annotations	Cellular Component	Cytoplasm Centrosome Extracellular Exosome	Golgi Membrane Autophagosome Membrane Cell Nucleoplasm Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Ciliary Pocket Membrane SNARE Complex Azurophil Granule Membrane Presynapse
	Molecular Function	SH3/SH2 Adaptor Activity Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Viral Process Positive Regulation Of Dendrite Extension	Exocytosis Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Cilium Assembly Membrane Fusion Autophagosome Maturation
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases			Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS		Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		77 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EGFR EPS15L1 EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	22 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 RASSF7 STX12 STX17 STX1A STX3 STX4 STX6 STX7 VAMP1 VAMP2 VAMP4 VAMP7
Entrez ID		50618	9342
HPRD ID		09193	11968
Ensembl ID		ENSG00000198399	ENSG00000099940
Uniprot IDs		A6H8W8 Q9NZM3	O95721
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO	4WY4
Enriched GO Terms of Interacting Partners?
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