PLA2G3 and TGFB1I1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PLA2G3	TGFB1I1
Description		phospholipase A2 group III	transforming growth factor beta 1 induced transcript 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Centriole Plasma Membrane Mast Cell Granule	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Metal Ion Binding Calcium-dependent Phospholipase A2 Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding
	Biological Process	Acrosome Assembly Phospholipid Metabolic Process Sperm Axoneme Assembly Lipid Catabolic Process Lipoxygenase Pathway Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Mast Cell Degranulation Arachidonic Acid Secretion Cilium Assembly	Transcription By RNA Polymerase II Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Substrate Adhesion-dependent Cell Spreading Endothelial Cell Migration Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PG
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756) Paclitaxel-induced neuropathy ( 23776197)	Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: PVR TGFB1I1	29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL
Entrez ID		50487	7041
HPRD ID		07144	03831
Ensembl ID		ENSG00000100078	ENSG00000140682
Uniprot IDs		Q9NZ20	A0A024QZE7 O43294
PDB IDs
Enriched GO Terms of Interacting Partners?
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