OVOL1 and MAFF

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		OVOL1	MAFF
Description		ovo like transcriptional repressor 1	MAF bZIP transcription factor F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Nucleoplasm Mitochondrion
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Kidney Development Spermatogenesis Mesoderm Development Epidermal Cell Differentiation Skin Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Germline Cell Cycle Switching, Mitotic To Meiotic Cell Cycle Negative Regulation Of Meiotic Cell Cycle Phase Transition Negative Regulation Of Stem Cell Proliferation	In Utero Embryonic Development Transcription By RNA Polymerase II Parturition Blood Coagulation Skeletal Muscle Cell Differentiation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Acne (severe) ( 24927181 30542056) Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic sensitization ( 30013184) Asthma ( 31361310 30929738 31619474) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Atopic dermatitis ( 23042114 22197932 26482879) Atopic march ( 26542096) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 29875488) Breast cancer ( 23535729) Chronic kidney disease ( 20383146) DNA methylation (variation) ( 23725790) Eczema ( 31361310) Estimated glomerular filtration rate ( 31451708) Medication use (diuretics) ( 31015401) Rosacea symptom severity ( 29771307) Serum uric acid levels ( 30993211) Systemic lupus erythematosus ( 26502338 28714469) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Urate levels ( 23263486)	Birth weight ( 31043758) Estimated glomerular filtration rate ( 31152163 31015462 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) HDL cholesterol ( 30275531) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 31562340) Triglyceride levels ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531)
Interacting Genes		1 interacting genes: MAFF	22 interacting genes: ATF3 BACH2 BATF2 BATF3 DDIT3 FOS GTF2A1L HDAC5 HOXD12 MAFG MAFIP NFE2 NFE2L1 NFE2L2 NFIL3 NR3C1 NRF1 OVOL1 PPARG PRRX1 PSAP SUN2
Entrez ID		5017	23764
HPRD ID		09080	05343
Ensembl ID		ENSG00000172818	ENSG00000185022
Uniprot IDs		G3V1B0 O14753	Q9ULX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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