OTX1 and KCNK16

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		OTX1	KCNK16
Description		orthodenticle homeobox 1	potassium two pore domain channel subfamily K member 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding	Voltage-gated Ion Channel Activity Potassium Channel Activity Protein Binding Potassium Ion Leak Channel Activity
	Biological Process	Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Diencephalon Morphogenesis	Potassium Ion Transport Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport
Pathways			TWIK-related alkaline pH activated K+ channel (TALK) Phase 4 - resting membrane potential
Drugs
Diseases
GWAS		Neurociticism ( 29500382) Regular attendance at a religious group ( 29970889) Risk-taking tendency (4-domain principal component model) ( 30643258)	Tenofovir clearance in HIV infection ( 26148204) Type 2 diabetes ( 24509480 22158537 30718926 28869590)
Interacting Genes		47 interacting genes: ADAMTSL4 CHIC2 CHRD COMP DPY30 FBLN5 GEMIN8P4 GRN KCNK16 KRT81 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B MTNR1B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4 TNS2 VWC2L	1 interacting genes: OTX1
Entrez ID		5013	83795
HPRD ID		08964	09565
Ensembl ID		ENSG00000115507	ENSG00000095981
Uniprot IDs		P32242	Q96T55
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?