OSM and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		OSM	TNNT1
Description		oncostatin M	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytosol Troponin Complex
	Molecular Function	Cytokine Activity Oncostatin-M Receptor Binding Protein Binding Growth Factor Activity	Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding
	Biological Process	Positive Regulation Of Acute Inflammatory Response Immune Response Multicellular Organism Development Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cytokine-mediated Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Oncostatin-M-mediated Signaling Pathway Regulation Of Growth Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of MAPK Cascade Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Inflammatory Response Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Regulation Of Hematopoietic Stem Cell Differentiation Positive Regulation Of Interleukin-17 Secretion	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction
Pathways		Interleukin-4 and Interleukin-13 signaling IL-6-type cytokine receptor ligand interactions	Striated Muscle Contraction
Drugs
Diseases			Nemaline myopathy
GWAS		Coronary artery disease ( 29212778) Delirium ( 29631748) Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 23128233) Nephropathy ( 21399633) Suicidal ideation ( 30145303) Tonsillectomy ( 27941131)	Height ( 31562340)
Interacting Genes		12 interacting genes: APP COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 IL6ST LIFR OSMR TNNT1 ZNF410	61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		5008	7138
HPRD ID		01300	01841
Ensembl ID		ENSG00000099985	ENSG00000105048
Uniprot IDs		B5MCX1 P13725	P13805
PDB IDs		1EVS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?