NPHS1 and KIRREL1

Number of citations of the paper that reports this interaction (PubMedID 12865409)
64

Data Source:
HPRD (in vivo, in vitro)

		NPHS1	KIRREL1
Description		NPHS1 adhesion molecule, nephrin	kirre like nephrin family adhesion molecule 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Slit Diaphragm Cell Projection Extracellular Exosome	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Cell Projection Membrane Dendritic Shaft Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Myosin Binding	Protein Binding Myosin Binding
	Biological Process	Cell Adhesion JNK Cascade Skeletal Muscle Tissue Development Myoblast Fusion Excretion Positive Regulation Of Actin Filament Polymerization Glomerular Basement Membrane Development Protein Localization To Synapse Regulation Of Excretion Glomerular Visceral Epithelial Cell Development	Negative Regulation Of Protein Phosphorylation Excretion Positive Regulation Of Actin Filament Polymerization Cell-cell Adhesion
Pathways		Nephrin family interactions Nephrin family interactions	Nephrin family interactions Nephrin family interactions
Drugs
Diseases		Nephrotic syndrome and focal segmental glomerulosclerosis
GWAS
Interacting Genes		11 interacting genes: CASK CD2AP FYN IQGAP1 KIRREL1 LYN NCK1 NCK2 NPHS2 SRC YES1	3 interacting genes: NPHS1 NPHS2 TJP1
Entrez ID		4868	55243
HPRD ID		04094	06306
Ensembl ID		ENSG00000161270	ENSG00000183853
Uniprot IDs		O60500	B4DN67 Q96J84
PDB IDs		4ZRT
Enriched GO Terms of Interacting Partners?
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