SNU13 and CDKN2C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		SNU13	CDKN2C
Description		small nuclear ribonucleoprotein 13	cyclin dependent kinase inhibitor 2C
Image
GO Annotations	Cellular Component	Dense Fibrillar Component Nucleus Nucleoplasm U4atac SnRNP Nucleolus Box C/D SnoRNP Complex Small-subunit Processome Protein-containing Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding SnoRNA Binding U4 SnRNA Binding U4atac SnRNA Binding U3 SnoRNA Binding Box C/D SnoRNA Binding ATPase Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	MRNA Splicing, Via Spliceosome Maturation Of LSU-rRNA Box C/D SnoRNP Assembly RRNA Processing Single Fertilization Maturation Of SSU-rRNA	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Cell Cycle Arrest Negative Regulation Of Cell Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Phosphorylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Oligodendrocyte Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs		Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin
Diseases
GWAS			Atrial fibrillation ( 29290336) Height ( 31562340) Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459) Ischemic stroke (large artery atherosclerosis) ( 26732560) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) QRS complex (12-leadsum) ( 27659466) QRS duration ( 27577874 21076409 27659466) Ventricular ectopy ( 29618737) Ventricular ectopy or supraventricular ectopy (pleiotropy) ( 29618737)
Interacting Genes		14 interacting genes: CDKN2C CHST1 GTF3C1 HSPB2 LRIF1 MAP1LC3B NUFIP1 POLA2 PPIH RAD17 RBM10 RHOU SNW1 XRCC6	51 interacting genes: AHCYL1 AKT1 ANGPTL4 APLP1 ARNT ATM ATR CCDC90B CCND2 CCNE1 CDK4 CDK6 CDKN2A CDKN2B COPS6 DRAP1 EPHA2 ERBB2 FGFR4 GDF9 GOPC GREB1 GRM1 LATS2 LNX2 LRIF1 LY96 MAP2K3 MAP2K5 MAPK10 MAPK8 MTA3 MYC NAGK NAT2 NF2 NIF3L1 PDGFRA PPP2CA RAF1 RBM48 REL SCGB2A2 SNU13 ST14 STK11 TCF12 TCF4 TLE1 TP53 UNC119
Entrez ID		4809	1031
HPRD ID		03197	04534
Ensembl ID		ENSG00000100138	ENSG00000123080
Uniprot IDs		P55769 Q6FHM6	P42773 Q6ICV4
PDB IDs		1E7K 2JNB 2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9	1BU9 1G3N 1IHB 1MX2 1MX4 1MX6
Enriched GO Terms of Interacting Partners?
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