NHLH2 and LMO3

Number of citations of the paper that reports this interaction (PubMedID 15930276)
43

Data Source:
BioGRID (genetic interference)
HPRD (in vivo)

		NHLH2	LMO3
Description		nescient helix-loop-helix 2	LIM domain only 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Mating Behavior Cell Differentiation Ovulation Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity	Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Heart rate variability traits (SDNN) ( 28610988) Metabolite levels ( 23823483)	Chronotype ( 30696823) Household income (MTAG) ( 31844048) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		2 interacting genes: HES1 LMO3	37 interacting genes: AIMP2 BANP BEND7 CARF CBY2 CCDC33 CCDC85B CEP170P1 CEP57L1 DVL2 FAM131C FBLIM1 FOS GABPB1 GOLGA2 HNRNPC HNRNPM IKZF1 KCTD1 KXD1 LDB1 LDB2 MBIP MDFI NBPF22P NHLH2 NUTM1 PHC2 PNMA1 RALYL RFX6 RORA SAMD3 SP4 TAX1BP1 ZBTB43 ZBTB8A
Entrez ID		4808	55885
HPRD ID		01213	11832
Ensembl ID		ENSG00000177551	ENSG00000048540
Uniprot IDs		A1PLF1 Q02577	A0A024RAT1 Q8TAP4 Q9NYC6
PDB IDs
Enriched GO Terms of Interacting Partners?
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