NGFR and MAGEH1

Number of citations of the paper that reports this interaction (PubMedID 12414813)
29

Data Source:
HPRD (in vivo)

		NGFR	MAGEH1
Description		nerve growth factor receptor	MAGE family member H1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Nucleoplasm Endosome Cytosol Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Cell Surface Postsynaptic Density Integral Component Of Membrane Growth Cone Dendritic Spine Perikaryon	Cytoplasm
	Molecular Function	Amyloid-beta Binding Transmembrane Signaling Receptor Activity Death Receptor Activity Protein Binding Calmodulin Binding Coreceptor Activity Rab GTPase Binding Ubiquitin Protein Ligase Binding Signaling Receptor Activity Neurotrophin Binding Nerve Growth Factor Binding	Protein Binding
	Biological Process	Cellular Glucose Homeostasis Intracellular Protein Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Rho Protein Signal Transduction Axon Guidance Central Nervous System Development Detection Of Temperature Stimulus Nerve Development Hair Follicle Morphogenesis Membrane Protein Intracellular Domain Proteolysis Circadian Regulation Of Gene Expression Dorsal Aorta Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Glucose Homeostasis Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Fibroblast Proliferation Negative Regulation Of Axonogenesis Positive Regulation Of Axonogenesis Neuron Apoptotic Process Negative Regulation Of Hair Follicle Development Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Cellular Response To Amyloid-beta Positive Regulation Of Apoptotic Signaling Pathway	Apoptotic Process
Pathways		Axonal growth inhibition (RHOA activation) NRAGE signals death through JNK p75NTR negatively regulates cell cycle via SC1 Ceramide signalling Regulated proteolysis of p75NTR NFG and proNGF binds to p75NTR NADE modulates death signalling NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus p75NTR recruits signalling complexes p75NTR recruits signalling complexes NF-kB is activated and signals survival Axonal growth stimulation
Drugs
Diseases
GWAS		Immune reponse to smallpox (secreted IL-2) ( 22610502) Lower body strength ( 27325353) Prostate cancer ( 23535732)	Smoking initiation ( 24665060)
Interacting Genes		48 interacting genes: ANXA7 BEX1 BEX3 BNIP3L CAV1 CD80 CDKN1A FSCN1 GRB2 H2AX IL2 KIDINS220 LINGO1 MAG MAGED1 MAGEH1 MAPK1 MAPK3 MDM2 NDN NFKBIB NGF NSMCE3 NTF4 NTRK1 NTRK2 NTRK3 PRKACB PTPN13 RCC1 RIPK2 RPN2 RTN4R SHC1 SMN1 SORT1 STMN2 TK1 TP53 TRA2B TRADD TRAF2 TRAF4 TRAF6 TRIM37 TTR UFD1 ZNF274	14 interacting genes: APP CDK5RAP2 ELN HMBOX1 KPNA2 MOAP1 NAP1L5 NGFR PIAS4 TADA3 TNFRSF1A TNIP1 TRIM41 ZSCAN9
Entrez ID		4804	28986
HPRD ID		01197	06633
Ensembl ID		ENSG00000064300	ENSG00000187601
Uniprot IDs		P08138	Q9H213
PDB IDs		2N80 2N83 2N97 3EWV 5ZGG
Enriched GO Terms of Interacting Partners?
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