NFKBIL1 and ADIPOR1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NFKBIL1	ADIPOR1
Description		NFKB inhibitor like 1	adiponectin receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding	Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity
	Biological Process	I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Toll-like Receptor Signaling Pathway Cytoplasmic Sequestering Of Transcription Factor Cellular Response To Lipopolysaccharide	Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Negative Regulation Of JAK-STAT Cascade Positive Regulation Of JAK-STAT Cascade Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of NIK/NF-kappaB Signaling
Pathways			AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Crohn's disease ( 23128233) Height ( 28552196) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Inflammatory bowel disease ( 28067908) Neonatal lupus ( 20662065) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Type 1 diabetes and autoimmune thyroid diseases ( 25936594) Type 2 diabetes ( 30054458) Ulcerative colitis ( 28067908)	Mean platelet volume ( 27863252)
Interacting Genes		4 interacting genes: ADIPOR1 C2orf88 CASP10 CLEC18C	6 interacting genes: APPL1 CEP350 DPH3 NAA20 NFKBIL1 STK11
Entrez ID		4795	51094
HPRD ID		07043	06402
Ensembl ID		ENSG00000204498	ENSG00000159346
Uniprot IDs		A0A0A0MRT5 A8K778 Q5STV6 Q9UBC1	Q96A54
PDB IDs			3WXV 5LXG
Enriched GO Terms of Interacting Partners?
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