NAB2 and TTC19

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NAB2	TTC19
Description		NGFI-A binding protein 2	tetratricopeptide repeat domain 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Mitochondrial Inner Membrane Centrosome Midbody Respiratory Chain
	Molecular Function	Transcription Corepressor Activity Protein Binding Transcription Factor Binding Identical Protein Binding	Protein Binding
	Biological Process	Endochondral Ossification Regulation Of Transcription, DNA-templated Schwann Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase III Myelination Regulation Of Epidermis Development Positive Regulation Of Tau-protein Kinase Activity	Mitotic Cytokinesis Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process
Pathways		NGF-stimulated transcription NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31361310 31619474 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Asthma or allergic disease (pleiotropy) ( 29785011) Bipolar disorder ( 31043756) IgE levels ( 22075330) Schizophrenia ( 25056061 29483656)
Interacting Genes		34 interacting genes: CCDC33 CCHCR1 CWF19L2 DGCR6 EGR1 EGR2 GCC1 JAKMIP2 KRT40 KRTAP10-3 KRTAP10-8 LENG1 LMNA MAPK3 MCM7 MDFI MORF4L1 NEDD9 NME7 NOTCH2NLA PHF1 PHOSPHO2 PIN1 RBPMS RFC5 SCNM1 SUMO1P1 TCEANC TCHP TGIF2LY TLE5 TTC19 ZBED8 ZMYND19	12 interacting genes: ATXN1 CCDC33 CHMP4A EIF4ENIF1 HPS6 IHO1 L3MBTL3 NAB2 REL SPRED1 UBA1 UPF3B
Entrez ID		4665	54902
HPRD ID		03854	07899
Ensembl ID		ENSG00000166886	ENSG00000011295
Uniprot IDs		Q15742	A0A024RD83 Q6DKK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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