MYOD1 and ID4

Number of citations of the paper that reports this interaction (PubMedID 11756408)
32

Data Source:
HPRD (two hybrid)

		MYOD1	ID4
Description		myogenic differentiation 1	inhibitor of DNA binding 4, HLH protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Myofibril	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Transcription Coactivator Activity Protein Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Nuclear Hormone Receptor Binding Protein Dimerization Activity E-box Binding Promoter-specific Chromatin Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding Protein Dimerization Activity Transcription Regulator Activity
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Myoblast Fusion Cellular Response To Starvation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Cell Differentiation Muscle Cell Fate Commitment Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Muscle Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II Negative Regulation Of Myoblast Proliferation	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Regulation Of Transcription By RNA Polymerase II Neuroblast Proliferation Positive Regulation Of Cell Proliferation Hippocampus Development Cerebral Cortex Neuron Differentiation Central Nervous System Myelination Cell Differentiation Circadian Regulation Of Gene Expression Cellular Protein Localization Fat Cell Differentiation Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Prostate Gland Epithelium Morphogenesis Prostate Gland Stromal Morphogenesis Seminal Vesicle Morphogenesis
Pathways		Myogenesis Myogenesis	NGF-stimulated transcription
Drugs
Diseases
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Age at voice drop ( 27182965) Age-related cognitive decline (attention/processing speed) (slope of z-scores) ( 30954325) Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Automobile speeding propensity ( 30643258) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronic obstructive pulmonary disease ( 30804561) Chronotype ( 30696823) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Endometriosis ( 23472165 28333195 28537267) Free thyroxine concentration ( 30367059) Height ( 28552196 20881960) Loneliness (multivariate analysis) ( 27629369) Response to statin therapy ( 20339536)
Interacting Genes		61 interacting genes: ASCL3 BHLHA15 BHLHE40 BHLHE41 C2orf88 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 FBXO32 HAND1 HDAC1 HEY1 HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 JUN KAT2B KAT5 KPNA3 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF3 TCF4 TWIST1	4 interacting genes: HES1 ID3 MYOD1 TCF4
Entrez ID		4654	3400
HPRD ID		01166	08995
Ensembl ID		ENSG00000129152	ENSG00000172201
Uniprot IDs		P15172	P47928
PDB IDs
Enriched GO Terms of Interacting Partners?
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