MST1 and RASSF1

Number of citations of the paper that reports this interaction (PubMedID 14729613)
20

Data Source:
BioGRID (two hybrid)

		MST1	RASSF1
Description		macrophage stimulating 1	Ras association domain family member 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Collagen-containing Extracellular Matrix	Spindle Pole Nucleus Cytoplasm Microtubule Organizing Center Microtubule Microtubule Cytoskeleton
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Receptor Tyrosine Kinase Binding	Protein Binding Zinc Ion Binding
	Biological Process	Proteolysis Regulation Of Macrophage Chemotaxis Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Histone H2A-S139 Phosphorylation Negative Regulation Of Gluconeogenesis Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of CAMP-dependent Protein Kinase Activity	Cell Cycle Arrest Ras Protein Signal Transduction Regulation Of Microtubule Cytoskeleton Organization
Pathways		Signaling by MST1
Drugs
Diseases			Non-small cell lung cancer Bladder cancer Nasopharyngeal cancer
GWAS		Blood protein levels ( 30072576 29875488 28240269) Body mass index ( 26426971) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 17554261 17554300 21102463) Extremely high intelligence ( 29520040) Feeling miserable ( 29500382) Inflammatory bowel disease ( 28067908 23128233) Primary sclerosing cholangitis ( 23603763 27992413 21151127) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Ulcerative colitis ( 19915572 28067908 20228799 25082827 21297633)	Schizophrenia ( 28991256 30285260) Sleep duration (short sleep) ( 30846698)
Interacting Genes		9 interacting genes: FOXO1 KLKB1 MOB1A MST1R RASSF1 SERPINA3 TNNC1 TNNI3 TNNT2	70 interacting genes: AKT1 ARAF ATM ATP2B4 ATR ATRX AURKA AURKB BRAF C7orf25 C8orf33 CCND2 CCNE1 CDC20 CDK4 CDK6 CDKN2A CDKN2B CLNK CNKSR1 DAXX DDB1 E4F1 EPHA2 ERBB2 EXOSC8 FGFR4 FZR1 GLIS2 GRM1 HRAS IGFBP5 KAT2A KCNE3 KDELR2 KDM1A LATS2 MAP1B MAP1S MAP2K3 MAP2K6 MAPK8 MDM2 MET MOAP1 MST1 MYC NF2 NUDT10 PRKDC RAF1 RASSF5 RELA RHOA RHOU SAV1 SMARCA4 STK11 STK3 STK4 SUV39H1 SUV39H2 TEAD2 TERT TNFRSF10A TNFRSF1A TSC1 TUBB TUBG1 XPA
Entrez ID		4485	11186
HPRD ID		00798	05470
Ensembl ID		ENSG00000173531	ENSG00000068028
Uniprot IDs		G3XAK1 P26927 Q53GN8	Q9NS23
PDB IDs		2ASU 4QT8	2KZU
Enriched GO Terms of Interacting Partners?
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