MLF1 and COPS3

Number of citations of the paper that reports this interaction (PubMedID 15861129)
31

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MLF1	COPS3
Description		myeloid leukemia factor 1	COP9 signalosome subunit 3
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cilium Ciliary Basal Body	Nucleoplasm Cytoplasm Cytosol COP9 Signalosome
	Molecular Function	DNA Binding Protein Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Myeloid Progenitor Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Arrest	Protein Deneddylation Nucleotide-excision Repair, DNA Damage Recognition In Utero Embryonic Development Transcription-coupled Nucleotide-excision Repair Ubiquitin-dependent Protein Catabolic Process Signal Transduction Response To Light Stimulus Post-translational Protein Modification
Pathways			DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Depression ( 29700475) Major depressive disorder ( 27479909) Sporadic neuroblastoma ( 28545128) Systolic blood pressure ( 30224653)
Interacting Genes		8 interacting genes: CENPU COP1 COPS3 GRIK5 MAGEA11 MEOX2 NRBP1 YWHAZ	24 interacting genes: ARAF CEBPE COPS2 COPS4 COPS5 COPS6 COPS7A COPS8 COPS9 CSNK2A1 CSNK2B CUL5 GPS1 IKBKB IKBKG IL1RN IRF5 ITGB2 LRP2BP MCPH1 MLF1 RAF1 SOS1 TP53
Entrez ID		4291	8533
HPRD ID		03239	07262
Ensembl ID		ENSG00000178053	ENSG00000141030
Uniprot IDs		A0A0S2Z4U8 A0A140VKD2 B2RD48 P58340 Q2TLE4 Q5HYH4	B4DN01 Q9UNS2
PDB IDs		3UAL 3UBW	4D10 4D18 4WSN 6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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