MFGE8 and TRIP13

		MFGE8	TRIP13
Description		milk fat globule EGF and factor V/VIII domain containing	thyroid hormone receptor interactor 13
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen External Side Of Plasma Membrane Membrane Extrinsic Component Of Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle	Male Germ Cell Nucleus Nucleus Chromosome
	Molecular Function	Phosphatidylserine Binding Integrin Binding Extracellular Matrix Structural Constituent Phosphatidylethanolamine Binding	Transcription Coregulator Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Angiogenesis Phagocytosis, Recognition Phagocytosis, Engulfment Cell Adhesion Single Fertilization Apoptotic Cell Clearance Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Phagocytosis	Oocyte Maturation Double-strand Break Repair Transcription By RNA Polymerase II Mitotic Spindle Assembly Checkpoint Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Meiotic Recombination Checkpoint Regulation Of Nucleic Acid-templated Transcription
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation Amyloid fiber formation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Coronary artery disease ( 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Height ( 31562340) Pulse pressure ( 27841878) Squamous cell lung carcinoma ( 28604730)	Pancreatic cancer ( 25086665)
Interacting Genes		7 interacting genes: LOXL1 MRPL46 MRPS11 PRLR PSTPIP1 TM6SF1 TRIP13	83 interacting genes: ADAM15 AMDHD2 ARL11 ARSA ASB13 BUB1B C11orf54 C4orf33 CARD14 CD99 CDC20 CFP COMT CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FBLN5 FBXO8 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 INTS11 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 KYAT1 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1 MAD2L1BP MEAK7 METTL15 MFGE8 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 NTAQ1 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA PRKN QARS1 RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TNRC6A TPT1 UBE2I VDR ZNF34 ZNF655
Entrez ID		4240	9319
HPRD ID		03789	05145
Ensembl ID		ENSG00000140545	ENSG00000071539
Uniprot IDs		B3KTQ2 B4E396 Q08431	Q15645
PDB IDs			5VQ9 5VQA 5WC2 6F0X
Enriched GO Terms of Interacting Partners?
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