MCF2 and GNA13

Number of citations of the paper that reports this interaction (PubMedID 11062019)
4

Data Source:
HPRD (in vivo, in vitro)

		MCF2	GNA13
Description		MCF.2 cell line derived transforming sequence	G protein subunit alpha 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Membrane	Cell Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Exosome
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding D5 Dopamine Receptor Binding Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Dendrite Development Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Cellular Response To Leukemia Inhibitory Factor	Branching Involved In Blood Vessel Morphogenesis In Utero Embryonic Development Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Regulation Of Cell Shape Cell Differentiation Platelet Activation Regulation Of Cell Migration Activation Of Phospholipase D Activity Positive Regulation Of Apoptotic Process Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Axonal growth inhibition (RHOA activation) NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events	NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events Thromboxane signalling through TP receptor Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	White matter microstructure (global fractional anisotropy) ( 24736177)
Interacting Genes		8 interacting genes: CDC42 ERCC3 GNA13 GNB1 RHOA RHOG STUB1 TNK2	31 interacting genes: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR
Entrez ID		4168	10672
HPRD ID		02406	05100
Ensembl ID		ENSG00000101977	ENSG00000120063
Uniprot IDs		B2R9S6 P10911	A0A024R8M0 Q14344
PDB IDs
Enriched GO Terms of Interacting Partners?
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