MBD1 and OASL

Number of citations of the paper that reports this interaction (PubMedID 14728690)
8

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MBD1	OASL
Description		methyl-CpG binding domain protein 1	2'-5'-oligoadenylate synthetase like
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding	2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding ATP Binding Thyroid Hormone Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Methylation-dependent Chromatin Silencing Transcription By RNA Polymerase II Heart Development Aging Neuron Differentiation Response To Nutrient Levels Response To Estradiol Response To Cocaine Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Astrocyte Differentiation	Response To Virus Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity
Pathways		SUMOylation of transcription cofactors	Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 28165464)	C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) N-glycan levels ( 21908519 21203500) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)
Interacting Genes		25 interacting genes: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SP1 SUV39H1 TENM1 ZNF512B	3 interacting genes: MBD1 SEZ6L2 THRA
Entrez ID		4152	8638
HPRD ID		01133	04473
Ensembl ID		ENSG00000141644	ENSG00000135114
Uniprot IDs		A8K654 B4DI41 B4DUR3 Q9UIS9	Q15646
PDB IDs		1D9N 1IG4 4D4W 5W9Q 6D1T	1WH3 4XQ7
Enriched GO Terms of Interacting Partners?
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