ARSL and NDN

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARSL	NDN
Description		arylsulfatase L	necdin, MAGE family member
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Golgi Apparatus Golgi Stack Extracellular Exosome	Nucleoplasm Centrosome Cytosol Cell Projection Perikaryon
	Molecular Function	Arylsulfatase Activity Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Gamma-tubulin Binding
	Biological Process	Skeletal System Development	Neuron Migration Respiratory System Process Nervous System Development Axonal Fasciculation Central Nervous System Development Negative Regulation Of Cell Proliferation Glial Cell Migration Post-embryonic Development Cytokine-mediated Signaling Pathway Sensory Perception Of Pain Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Neurotrophin TRK Receptor Signaling Pathway Axon Extension Multicellular Organismal Homeostasis Genetic Imprinting
Pathways		Glycosphingolipid metabolism The activation of arylsulfatases	Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases			Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS			Depressive symptoms (SSRI exposure interaction) ( 25649181) Plasma anti-thyroid peroxidase levels ( 29678681) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		4 interacting genes: COQ6 NDN TMEM259 TNK2	47 interacting genes: APBB1IP ARSL BLOC1S6 CALCOCO2 CCDC136 CDR2 DTNBP1 E2F1 E2F4 EEF1AKMT1 EGFR EID1 EPAS1 FAM131C FSD2 FXR2 GKAP1 GOLGA2 HIF1A HNRNPU IFFO1 IL1A IL32 IRS4 LAX1 LPXN MIER2 MKRN2 MPP6 MYG1 NEFL NGFR NUBP1 NUCB1 NUCB2 P4HA3 PJA1 PPARGC1A PPFIA1 SERTAD3 SIRT1 SSX2IP TFIP11 TP53 U2AF1 ZBTB1 ZBTB7B
Entrez ID		415	4692
HPRD ID		02171	03667
Ensembl ID		ENSG00000157399	ENSG00000182636
Uniprot IDs		A0A5F9ZHX8 A1L484 B7Z1M0 B7Z6V4 F5GYY5 F5H324 P51690	Q99608 X5D982
PDB IDs
Enriched GO Terms of Interacting Partners?
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